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PANACEA Newsletter - Issue 3

PANACEA Newsletter - Issue 3
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Editor-in-chief: Maurane Vanderzwalm

‍Issue 3 - 24 August 2023


Lunch Workshop at EUROMAR 2023 - July 11, 2023 - Glasgow, Scotland

PANACEA organized a lunch workshop at EUROMAR 2023 in Glasgow. Around 70 people attended.

Steven Brown from the University of Warwick introduced the PANACEA network, while Anne Lesage and Guido Pintacuda, project coordinators gave an overview of the access activities. Jennifer Gomez, local operator at the Radboud University and Trent Franks from the University of Warwick presented transnational access from the facilities point of view. Then, Frédéric Blanc from the University of Liverpool, and user of PANACEA, presented his perspectives as a user, and how PANACEA helped him through his own projects. Then, Thomas Vosegaard from the Aahrus University gave a talk on the EasyNMR interface, developed through the PANACEA project and Kristof Grohe from Bruker Biospin revealed progress on new MAS NMR probes.Finally, upcoming events were presented, especially our second annual user meeting which will be held in Florence, Italy, from 15-16 of November 2023.

Thank you all for attending!



A 19F HFX prototype probe under development


The uniqueness of this triple-channel low temperature solid-state DNP probe lies in separate radiofrequency channels for 1H and 19F Larmor frequency, thus enabling independent pulsing on both proton and fluorine nuclei. This allows for acquiring fluorine spectra with much better sensitivity and resolution. The above mentioned features make this newly developed probe an indispensable tool for investigating pharmaceutical formulations, which often contain fluorine. Combined with the dynamic nuclear polarization (DNP) enhancement of the NMR signal, the future prospects are to perform in-cell detection of pharmaceuticals upon natural uptake.




PANACEA Fellows 

Student profile: Mária ŠOLTÉSOVÁ, Swedish NMR Centre, University of Gothenburg, Sweden

Q: Why did you decide to apply for a post-doc position at the Swedish NMR Centre?

A: When I saw the PANACEA post-doc advertisement, I immediately recognized this as an exciting opportunity to be involved in cutting-edge research. Using the state-of-the-art equipment of the Swedish NMR Centre at the University of Gothenburg and developing new methods of solid-state DNP to study structure and interactions of pharmaceuticals seemed to me like challenging research with high impact. 

Q: When did you choose a topic related with solid-state DNP NMR?

A: I have a long experience with NMR as such, and solid-state DNP NMR is a fast-developing field with a huge application potential. 

Q: Do you have a science hero or mentor? 

A: I was always inspired by women in science, and the quote of Marie Skłodowska-Curie "Nothing in life is to be feared. It is only to be understood" was my guide through a large part of my scientific career. 

Q: What did you want to be when you were a child? 
A: I wanted to be a teacher. And this childhood dream has been fulfilled beyond my expectation, because as a researcher, I can spread the knowledge through publishing my research and provide education as a lecturer and a supervisor. 






Florence scenic view

PANACEA 2nd annual user meeting and industrial day, Florence - 15-16 November 2023

The second annual user meeting and industrial day of PANACEA will be held in Florence (IT). This will be a two-day event dedicated to our users and our industrial partners. The conference will take place at the Auditorium Santa Apollonia, downtown of Florence in Italy. More information is coming soon here. Save the date!


PANACEA Summer school - 16-21 June 2024

PANACEA is organizing a solid-state NMR Summer School in Venice, directed towards graduate students, post-doctoral fellows, other early-stage researchers and technical staff from both academia and industry. Training will involve a variety of experts, and will take the form of lectures, tutorials, discussions supplemented by guided problem-solving sessions, so to allow participants to acquire a deep understanding of the possibilities (and limitations) of the various techniques of solid-state NMR (Hamiltonians in solid-state NMR, anisotropic interactions, tensor description, magic angle spinning and time-dependent Hamiltonians, average Hamiltonian and Floquet theory, principles of recoupling and decoupling under MAS, principles of hyperpolarized NMR, paramagnetic NMR, relaxation in the solid-state, implementation of phase cycling and quadrature detection). The summer school will be located in San Servolo island. Save the date! More information can be found on our webpage


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