NEWSLETTER OF H2020 - INFRAIA-02-2020 "PANACEA" |
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Editor-in-chief: Raphaële Coulon |
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| |  Spring hands-on workshop Lyon, France - May 19th-23rd 2025
The PANACEA Spring Hands-on Workshop concluded successfully on Friday 23rd of May, marking the end of a dynamic and enriching week dedicated to advanced training in pNMR, DNP and related spectroscopic techniques.
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The workshop brought together 30 participants, 7 expert speakers, and 9 supervisors from accross Europe and beyond. This intensive program offered a balanced mix of theoretical lectures, experimental sessions, and collaborative discussions. Â
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| PANACEA key numbers- 1650 access days
- 27 spectrometers
- > 200 chemistry-related projects
| - 4 user meetings
- 3 hands-on trainings
- 1 NMR summer School
| - 3 industry-targeted workshops
- 32 taster days for industrials
- 8 summer fellowships for students
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Exciting Joint Research Activity Publication- Advances of 1H–19F CP-MAS-DNP for pharmeceutical formulations
| ‍Pharmaceutical research is an excellent  area where solid-state NMR has a large societal impact. Â
The 2025 PANACEA publication showcases the integration of innovative probe technology with the study of advanced pharmaceutical formulations. It introduces a novel dynamic nuclear polarization (DNP) probe leveraging the ^19F nucleus, commonly present in commercial active pharmaceutical ingredients (APIs), to enable detailed analysis of drug formulations. Â
The study presents results for a commercially relevant API in both its pure powder form and its formulation within loaded polymeric nanoparticles. By transferring hyperpolarization from ^1H to ^19F nuclei using cross-polarization, and taking advantage of the faster build-up times of DNP-enhanced ^1H polarization, the approach allows for reduced recycle delays and significantly improved sensitivity and efficiency. The unique triple-channel, low-temperature, solid-state DNP-NMR probe—with independent radiofrequency channels for ^1H and ^19F—permits separate pulsing and superior acquisition of fluorine spectra in terms of sensitivity and resolution.
| ‍M. Šoltésová, A. C. Pinon, F. Aussenac, J. Schlagnitweit, C. Reiter, A. Purea, R. Melzi e, F. Engelke, D. Martin, S. Krambeck, A. Biscans, E. Kay, L. Emsley and S. Schantz, 1H–19F cross-polarization magic angle spinning dynamic nuclear polarization NMR investigation of advanced pharmaceutical formulations J. Magn. Reson. 371, 107827, 2025. |
| | Â Meet the PANACEA team at EUROMAR 2025!Oulu, Finland - July 6th-10th 2025 Â
Find out the latest developments in the Joint Research Activities, learn more about how you get access to 27 uniquely-equipped solid-state NMR instruments through our PANACEA Transnational Access scheme and ask any questions to our experts scientists. Â
The PANACEA booth will be located in the exhibition space at the main congress venue as part of one of the events' sponsors, come and meet us at booth 1. Â
See you at EUROMAR 2025 in Oulu! |
| |  Summer Research Visits to MagLab! Tallahassee, Florida - August,18th-29th 2025  The PANACEA consortium is excited to announce a summer research visit opportunity at the National High Magnetic Field Laboratory (MagLab) in tallahassee, Florida. Â
This exchange scheme is open to 8 motivated undergraduate, Master or PhD students with a keen interest in conducting supervised research in solid-state NMR and MAS-DNP-NMR. Â
These fully funded summer research visits provide a unique opportunity for highly motivated young researchers and students at different career stages, backgrounds and geographical origins to visit the MagLab and be part of an internationally leading research environment. Â
Read more... |
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